Correlations between Time, Latissimus Dorsi Wrap Properties and Systolic Assistance in Demand Dynamic Cardiomyoplasty?

A certain systolic assistance in Demand Dynamic Cardiomyoplasty (DDCMP) has been suggested. We here evaluate relations between muscular properties of Latissimus Dorsi wrap (LDW) and systolic function using the doppler flow wire combined with LDW mechanogram. On the basis of previous study, we divided the patients in two groups on the time between intervention and start of demand protocol (group 1: 12 months and group 2: 42 ± 21.6 months). A comparative study with a correlation analysis including time variables and the increase in maximal peak aortic velocity (MPAV) among not assisted and assisted beats was made. Time from the intervention (dyn-time) is similar. NYHA class, time between intervention and start of demand protocol (dyn/dem-time) and time from start of demand protocol (dem-time) were statistically different (p < 0.05). The increase in MPAV was significatively higher in group 1. A linear correlation has been found between the increase in MPAV and dem-time (r = 0.82), NYHA class and dyn/dem-time (r = 0.76), tetanic fusion frequency and dyn/dem-time (r = 0.99), increase in MPAV and tetanic fusion frequency (r = 0.73). In DDCMP systolic assistance is correlated to speed of LDW rapidity and time of demand stimulation. Long time continuous stimulation alters functional performance of LDW and lowers cardiac assistance. Demand stimulation protocol maintains over time contractile properties of the wrap and increases muscle performance.